唑尼沙胺
唑尼沙胺
唑尼沙胺;佐尼沙胺
Zonisamide
唑尼沙胺;佐尼沙胺
Zonisamide
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产品编号: CZR700000
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CAS号: 68291-97-4
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分子式:C8H8N2O3S
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分子量:212.23
英文别名:
1,2-Benzisoxazole-3-methanesulfonamide; 3-(Sulfamoylmethyl)-1,2-benzisoxazole; AD 810;
熔点:
160-163°C
可溶性:
DMSO, Ethanol, Ethyl Acetate, Methanol
性状:
White to Off-White Solid
SMILES:
C1N=CN(CC(P(=O)(O)O)(O)P(=O)(O)O)C=1
储存条件:
Refrigerator
参考文献:
Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980), Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987), Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993), Sorkin, E.M., et al.: Drugs, 45, 760 (1993),
Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant.
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