扎普司特
扎普司特
Zaprinast
扎普司特
Zaprinast
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产品编号： CZR150000
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CAS号： 37762-06-4
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分子式：C13H13N5O2
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分子量：271.3
英文别名：
3,6-dihydro-5-(2-propoxyphenyl)-
熔点：
237-238°C dec.
可溶性：
DMSO, Methanol
性状：
Pale Pink Solid
SMILES：
CC1=CC=C(NC(C(NC2CC(C)(C)NC(C)(C)C2)=O)=O)C=C1
储存条件：
-20˚C Freezer
参考文献：
Burns, F., et al.: Biochem. J., 238, 487 (1992), Lugnier, C., et al.: Am. J. Physiol., 262, H654 (1992),
A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of atrial natriuretic factor (ANF) through the activation of PKG (cGMP dependent protein kinase), such inhibitors may display vasodilating, relaxant, and diuretic effects. These compounds may prove useful in treating hypertension and congestive heart failure.
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