维生素D3
维生素D3
Vitamin D3
维生素D3
Vitamin D3
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产品编号： CVR676045
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CAS号： 67-97-0
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分子式：C27H44O
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分子量：384.64
英文别名：
(3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; Cholecalciferol; Duphafral D3 1000; Delsterol; Deparal;
熔点：
82-84°C
可溶性：
Acetone, Chloroform, Ethyl Acetate
性状：
White to Off-White Solid
SMILES：
CS(C1C=CC(C2COC(=O)C=2C2C([2H])=C([2H])C([2H])=C([2H])C=2[2H])=CC=1)(=O)=O
储存条件：
Amber Vial, -20°C Freezer, Under Inert Atmosphere
参考文献：
Haussler, R., et al.: J. Biol. Chem., 247, 2328 (1972), Holick, M.F., Rec. Res. Canc. Res., 164, 3 (2003), Palmer, H.G., et al.: Cancer Res., 63, 7799 (2003), Welsh, J., et al.: J. Nutr., 133, 2425S (2003),
The vitamin that mediates intestinal calcium absorbtion, bone calcium metabolism and probably, muscle activity. Occurs in and is isolated from fish liver oils. Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
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