凡德他尼-d4
凡德他尼-d4
Vandetanib-d4
凡德他尼-d4
Vandetanib-d4
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产品编号： CVR097102
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CAS号： 1215100-18-7
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分子式：C22H20D4BrFN4O2
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分子量：479.38
英文别名：
ZD 6474-d4; Zactima-d4
参考文献：
Bruns, C., et al.: Clin. Cancer Res., 6, 1936 (2000); Hennequin, L., et al.: J. Med. Chem., 45, 1300 (2002); Park, M., et al.: J. Biol. Chem., 278, 50624 (2003); Arao, T., et al.: Cancer Res., 64, 9101 (2004); Prueitt, R., et al.: Int. J. Cancer, 120, 796
A labelled Vandetanib; a once-daily oral inhibitor of vascular endothelial growth factor receptor-2 and epidermal growth factor receptor kinase activity. The activity of vandetanib plus docetaxel was assessed in patients with previously treated non-small-cell lung cancer (NSCLC).
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