UNC-926 Hydochloride
L3MBTL13XMBT-H4K20me1抑制剂；(3-溴苯基)[4-(1-吡咯烷基)-1-哌啶基]甲酮盐酸盐
UNC-926 Hydochloride
L3MBTL13XMBT-H4K20me1抑制剂；(3-溴苯基)[4-(1-吡咯烷基)-1-哌啶基]甲酮盐酸盐
UNC-926 Hydochloride
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产品编号： CUR712500
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CAS号： 1184136-10-4
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分子式：C16H22BrClN2O
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分子量：373.72
英文别名：
(3-Bromophenyl)[4-(1-pyrrolidinyl)-1-piperidinyl]methanone Hydochloride
SMILES：
O=[N+](C1=CC=CC=C1C1=CC=C(/C=C2\C(=O)N(C3=CC=CC=C3)C(=S)N(C3=CC=CC=C3)C\2=O)O1)[O-]
参考文献：
Herold, et al.: Med. Chem. Comm., 3, 45 (2012),
UNC-926 is a methyl-lysine reader antagonist; binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM). UNC-926 selectively inhibits the interaction between L3MBTL13XMBT-H4K20me1 in a peptide pull down assay.
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