UBP-301
海人酸受体拮抗剂；(αS)-α-氨基-3-[(4-羧基苯基)甲基]-3,4-二氢-5-碘-2,4-二酮代-1(2H)-嘧啶丙酸
UBP-301
海人酸受体拮抗剂；(αS)-α-氨基-3-[(4-羧基苯基)甲基]-3,4-二氢-5-碘-2,4-二酮代-1(2H)-嘧啶丙酸
UBP-301
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产品编号： CUR103500
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CAS号： 569371-10-4
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分子式：C15H14In3O6
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分子量：459.19
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EINECES：205-819-9
英文别名：
(αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
SMILES：
OC([C@H](Cc1c[nH]c2ccccc12)N)=O
参考文献：
Fletcher, E., et al.: Pharmacol. Ther., 70, 65 (1996), Bleakman, D., et al.: Neuropharmacology, 37, 1187 (1998), Chittajallu, R., et al.: Trends Pharmacol. Sci., 20, 26 (1999), Valgeirsson, J., et al.: J. Med. Chem., 47, 6948 (2004),
UBP 301 is an antagonist of kainate receptors. UBP 301 is the N3-4-carboxybenzyl substituted analog II of Willardiine, which was found to be equipotent at AMPA and GLUK5-containing kainate receptors in the neonatal rat spinal cord.
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