(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-三-{[叔丁基(二甲基)硅基]氧}-1-羟基-4,4,6,8,12,16-六甲基-17-(2-甲基-1,3-噻唑-4-基)十七碳-12,16-二烯-5-酮
埃博霉素中间体；(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-三-{[叔丁基(二甲基)硅基]氧}-1-羟基-4,4,6,8,12,16-六甲基-17-(2-甲基-1,3-噻唑-4-基)十七碳-12,16-二烯-5-酮
(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-Tris-{[tert-butyl(dimethyl)silyl]oxy}-1-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)heptadeca-12,16-dien-5-one
埃博霉素中间体；(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-三-{[叔丁基(二甲基)硅基]氧}-1-羟基-4,4,6,8,12,16-六甲基-17-(2-甲基-1,3-噻唑-4-基)十七碳-12,16-二烯-5-酮
(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-Tris-{[tert-butyl(dimethyl)silyl]oxy}-1-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)heptadeca-12,16-dien-5-one
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产品编号： CTR876625
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CAS号： 193146-53-1
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分子式：C45H87NO5SSi3
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分子量：838.5
英文别名：
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可溶性：
Acetone, Dichloromethane, Ethanol, Ethyl Acetate, Methanol
性状：
Colourless Oil
SMILES：
COC(=O)C(NC(=O)C1C=CC=CC=1)C/C(/NC(=O)C1C=CC=CC=1)=C/NC(=O)C1C=CC=CC=1
参考文献：
Hoee, G., et al.: Pure Appl. Chem., 71, 11, 2019 (1999), Giannakakou, P., et al.: Proc. Natl. Acad. Sci. USA, 97, 2904 (2000)
An intermediate in the synthesis of Epothilones. Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical
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