N-三氟乙酰秋水仙胺
N-三氟乙酰基-N-甲基-去乙酰秋水仙碱；N-三氟乙酰地美可辛
N-Trifluoroacetyldemecolcine
N-三氟乙酰基-N-甲基-去乙酰秋水仙碱；N-三氟乙酰地美可辛
N-Trifluoroacetyldemecolcine
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产品编号： CTR789510
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CAS号： 71295-35-7
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分子式：C23H24F3NO6
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分子量：467.43
英文别名：
N-Trifluoroacetyl-N-methyl-deacetylcolchicine
可溶性：
Chloromethane, Dichlormethane, DMSO, Methanol
性状：
Yellow Solid
SMILES：
CC([C@]1(C[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](NC(C(F)(F)F)=O)C2)C2=C(C3C(=O)C4C(=CC=CC=4OC)C(=O)C=3C(O)=C2C1)O)O)=O
参考文献：
Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pa
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