曲西立滨
曲西立滨
Triciribine
曲西立滨
Triciribine
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产品编号： CTR774245
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CAS号： 35943-35-2
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分子式：C13H16N6O4
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分子量：320.3
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EINECES：202-273-3
英文别名：
1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine;
6-Amino-4-methyl-8-(β-D-ribofuranosyl)-4H,8H-pyrrolo[4,3,2-de]pyrimido[4,5-c]pyridazine; API 2; NSC 154020; TCN;
SMILES：
ClC1C=C(Cl)C(Cl)=CC=1OCC(O)=O
参考文献：
Garrett, C.R. et al.: Invest. New Drugs, 29, 1381 (2011); Ptak, R.G. et al.: AIDS Res. Human Retrovir., 14, 1315 (1998); Bennett, L.L. et al.: BIochem. Pharmacol., 27, 233 (1978);
Triciribine is an antitumor tricyclic nucleoside. Triciribine acts as a potent, small-molecule inhibitor of AKT phosphorylation in subjects with solid tumors contining activated AKT. Triciribine is also a selective inhibitor of HIV-1 and HIV-2, including
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