Tosedostat
金属酶抑制剂
Tosedostat
金属酶抑制剂
Tosedostat
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产品编号： CTR549000
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CAS号： 238750-77-1
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分子式：C21H30N2O6
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分子量：406.47
英文别名：
CHR-2797；(αS)-α-[[(2R)-2-[(1S)-1-Hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]amino]benzeneacetic Acid Cyclopentyl Ester
SMILES：
O1[C@@]2(COS(=O)(=O)N)OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O[C@H]2[C@@H]2OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O[C@@H]2C1
参考文献：
Sato, Y., et al.: Biol. Pharm. Bull., 27, 772 (2004), Saveanu, L., et al.: Nat. Immunol., 6, 689
CHR-2797 is a novel metalloenzyme inhibitor that is converted into a pharmacological active acid product (CHR-79888) inside cells. CHR-2797 exerts antiproliferative effects against a range of tumor cell lines in vitro and in vivo and shows selectivity fo
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