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毒胡萝卜素
毒胡萝卜素
Thapsigargin
  • 产品编号: CTR339250

  • CAS号: 67526-95-8

  • 分子式:C34H50O12

  • 分子量:650.75

英文别名:
(-)-Thapsigargin
熔点:
84-90°C
可溶性:
Chloroform
性状:
Off-White Solid
SMILES:
SCCNS(C1C=CC(C2C3C=C4CCCN5C4=C(CCC5)C=3OC3=C4CCC[N+]5=C4C(=CC=23)CCC5)=C(S([O-])(=O)=O)C=1)(=O)=O
储存条件:
-20˚C Freezer
参考文献:
Treiman, M. et al.: Trends Pharmacol. Sci., 19, 131 (1998); Korge, P. et al.: Eur. J. Biochem., 265, 273 (1999); Tsukamoto, A. Cell Biol. Int., 17, 969 (1993); Kutinova C.N. et al.: Cell Biol. Toxicol., 23, 337 (2007);
A widely used inhibitor of the ubiquitous sarco-endoplasmic reticulum Ca(2+)-ATPases in mammalian cells. It acts as a potent, cell-permeable, IP3-independent intracellular calcium releaser that blocks the transient increase in intracellular Ca2+ induced b
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