Tanogitran Dihydrochloride
N-[(1R)-1-[2-[[[4-(氨基亚氨基甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]-1-甲基-2-酮基-2-(1-吡咯烷基)乙基]甘氨酸盐酸盐
Tanogitran Dihydrochloride
N-[(1R)-1-[2-[[[4-(氨基亚氨基甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]-1-甲基-2-酮基-2-(1-吡咯烷基)乙基]甘氨酸盐酸盐
Tanogitran Dihydrochloride
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产品编号： CTR006750
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CAS号： 253796-69-9
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分子式：C25H33Cl2N7O3
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分子量：550.48
英文别名：
BIBT 986 Dihydrochloride
参考文献：
Gomerz-Outes, A. et al.: Ther. Adv. Cardiovasc. Dis., 5, 33 (2011);
A novel synthetic, specific, direct, competitive and reversible inhibitor of both, FXa (Ki 26 nM) and thrombin (K i=2.7 nM). It showed a high anticoagulant potency in preclinical models of venous thrombosis in rats and rabbits.
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