盐酸他沙利定
盐酸他沙利定
Talsaclidine Hydrochloride
盐酸他沙利定
Talsaclidine Hydrochloride
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产品编号： CTR005601
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分子式：C10H16ClNO
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分子量：201.69
英文别名：
(R)-3-(2-Propynyloxy)-1-azabicyclo[2.2.2]octane Hydrochloride;
熔点：
138-142°C
可溶性：
Chloroform, Methanol
性状：
Beige Solid
SMILES：
O=C(NC1=C(F)C=CC(OC2C=CC3N=C(SC=3C=2C#N)NC(C2CC2)=O)=C1)CC1C=CC=C(C(F)(F)F)C=1
参考文献：
Hock, et al.: Amyloid, 10(1), 1 (2003), Moreau, M., et al.: J. Pharmacol. Sci., 99, 6
Talsaclidine, a novel M1-receptor selective muscarinic agonist for cholinergic substitution therapy of Alzheimer's disease. Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with
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