他匹莫德
他匹莫德
消旋坦索洛新盐酸盐;消旋坦洛新盐酸盐;消旋坦索罗辛盐酸盐
Talmapimod
消旋坦索洛新盐酸盐;消旋坦洛新盐酸盐;消旋坦索罗辛盐酸盐
Talmapimod
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产品编号: CTR005550
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CAS号: 309913-83-5
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分子式:C20H29ClN2O5S
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分子量:444.97
英文别名:
5-[2-[[2-(-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide Hydrochloride; Flomax; Harnal; Omnic; Pradif; YM 12617-1; YM 617; Yutanal;
SMILES:
FC1C=CC(CN2C[C@@H](C)N(C(C3=C(Cl)C=C4C(C(C(C(N(C)C)=O)=O)=CN4C)=C3)=O)C[C@@H]2C)=CC=1
参考文献:
Medicherla, S. et al.: Antincancer Res., 28, 3827 (2008); Genovese, M.S. et al.: J. Rheumatol., 38, 846 (2011); Medicherla, S. et al.: J. Inflam. Res., 3, 9 (2010);
Talmapimod is a p38 mitogen-activated protein (MAP) kinase inhibitor. Talmapimod reduced human myeloma cell growth in vivo both at early and advanced phases of the disease in mouse xenograft models. Talmapimod that blocks tumor necrosis factor-α, interleu
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