甲磺司特
甲磺司特
Suplatast Tosylate
甲磺司特
Suplatast Tosylate
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产品编号： CSR841000
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CAS号： 94055-76-2
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分子式：C23H33NO7S2
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分子量：499.64
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EINECES：223-772-2
英文别名：
[3-[[4-(3-ethoxy-2-hydroxypropoxy)phenyl]amino]-3-oxopropyl]dimethylsulfonium 4-Methylbenzenesulfonate;
(±)-[2-[4-(3-Ethoxy-2-hydroxypropoxy)phenylcarbamoyl]ethyl]dimethylsulfonium p-toluenesulfonate; IPD 1151T; Suplatast tosilate;
SMILES：
C(C1=CC(S(O)(=O)=O)=C(OC)C=C1O)(=O)C1C=CC=CC=1
参考文献：
Koda, A. et al.: Agents Act. Supp., 34, 369 (1991); Koda, A. et al.: Prog. Allergy Clin. Immunol., Proc. Int. Congr. Allergol. Clin. Immunol., 14, 41 (1992); Shichijo, M. et al.: Jap. J. Pharmacol., 79, 501 (1999);
Suplatast Tosylate is an antiallergic drug. Suplatast Tosylate inhibits antigen-induced histamine release from mast cells as well as IgE antibody formation. Suplatast Tosylate suppresses interleukin (IL)-4 release from T cells, however in human peripheral basophils, Suplatast Tosylate inhibited the antigen-induced release of IL-13 but not IL-4.
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