Sumanirole Maleate
马来酸舒马尼罗
Sumanirole Maleate
马来酸舒马尼罗
Sumanirole Maleate
-
产品编号： CSR790700
-
CAS号： 179386-43-7
-
分子式：C15H17N3O5
-
分子量：319.31
英文别名：
(5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-Butenedioate; (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-
2(1H)-one (2Z)-2-Butenedioate;
熔点：
206-208°C (dec.)
可溶性：
DMSO, Methanol
性状：
Off-White to Light Beige Solid
SMILES：
ICC(NC1=CC=C(C(ON2C(=O)CC(S(O[Na])(=O)=O)C2=O)=O)C=C1)=O
储存条件：
Refrigerator
参考文献：
McCall, et al.: J. Pharmacol. Exp. Ther., 314 1248 (2005), Stephenson, et al.: J. Pharmacol. Exp. Ther., 314 1257 (2005),
Sumanirole is a high affinity D2 receptor agonist (EC50 values are between 17 and 75 nM in cell-based assays). Sumanirole displays >200-fold selectivity for the D2 receptor against other dopamine receptor subtypes (Ki values are 9.0, 1940, >2190 and >7140 for D2, D3, D4 and D1 receptors respectively). Sumanirole exhibits antiParkinsonian activity similar to Ropinirole (R641000).
搜索质检报告(COA)
搜索MSDS
