伏立诺他
伏立诺他
伏立诺他;N-羟基-N’-苯基辛二酰胺
Suberoylanilide Hydroxamic Acid
伏立诺他;N-羟基-N’-苯基辛二酰胺
Suberoylanilide Hydroxamic Acid
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产品编号: CSR688700
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CAS号: 149647-78-9
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分子式:C14H20N2O3
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分子量:264.32
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EINECES:202-851-5
英文别名:
SAHA;Vorinostat;Zolinza
熔点:
161-162°C
可溶性:
DMSO, Methanol
性状:
White Solid
SMILES:
C=CC1=CC=CC=C1
储存条件:
-20°C Freezer
参考文献:
Richon, V.M., et al.: Proc. Natl. Acad.Sci. USA, 95, 3003 (1988), Munster, P.N., et al.: Cancer Res., 61, 8492 (2001), Deroanne, C.F., et al.: Oncogene, 21, 247 (2002),
Suberoylanilide Hydroxamic Acid is a potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Suberoylanilide Hydroxamic Acid displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Suberoylanilide Hydroxamic Acid induces differentiation in uman breast cancer cells.
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