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SMER 28
6-溴-N-2-丙烯-4-喹唑啉胺
SMER-28
  • 产品编号: CSR565000

  • CAS号: 307538-42-7

  • 分子式:C11H10BrN3

  • 分子量:264.12

英文别名:
6-Bromo-N-2-propenyl-4-Quinazolinamine
参考文献:
Renna, et al.: J. Biol. Chem., 285, 11061 (2010); Sarkar, et al.: Nat. Chem. Biol., 3, 331 (2010);
SMER 28 is a positive regulator of autophagy in a mechanism independent from the mTOR pathway. SMER 28 increases autophagosome synthesis and enhances clearance of model autophagy substrates such as A53T α-synuclein associated with Huntington's disease.
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