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SB-612111 盐酸盐
nociceptin/orphanin FQ受体拮抗剂;(5S,7S)-7-[[4-(2,6-二氯苯基)-1-哌啶基]甲基]-6,7,8,9-四氢-1-甲基-5H-环并环庚烯-5-醇盐酸盐
SB 612111 Hydrochloride
  • 产品编号: CSR154750

  • 相关CAS号:371980-98-2(单体)

  • 分子式:C24H30Cl3NO

  • 分子量:454.86

英文别名:
(5S,7S)-7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-ol Hydrochloride
参考文献:
Rizzi, A. et al.: J. Pharmacol. Exp. Therap., 321, 968 (2007); Liao, Y. et al.: Eur. J. Pharmacol., 657, 84 (2011); Zaratin. P.F. et al.: J. Pharmacol. Exp. Therap., 308, 454 (2004);
A selective nociceptin/orphanin FQ receptor antagonist. A potentially useful adjunct to chronic pain therapy with opioids and can be used to treat conditions in which thermal hyperalgesia is a significant component of the pain response.
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