SB-202190 盐酸盐
p38MAP激酶抑制剂；4-[4-(4-氟苯基)-5-(4-吡啶基)-1H-咪唑-2-基]苯酚盐酸盐
SB 202190 Hydrochloride
p38MAP激酶抑制剂；4-[4-(4-氟苯基)-5-(4-吡啶基)-1H-咪唑-2-基]苯酚盐酸盐
SB 202190 Hydrochloride
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产品编号： CSR154500
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CAS号： 350228-36-3
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分子式：C20H15ClFN3O
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分子量：367.8
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EINECES：203-538-6
英文别名：
4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol Monohydrochloride
SMILES：
N(CC(O)=O)C
参考文献：
Horstmann, S. et al.: J. Neurosci. Res., 52, 483 (1998); Zhang, F. et al.: Zhong. Yao. Tong., 18, 512 (2002); Wang, J. et al.: Nanj. Yike Dax. Xue., 29, 840 (2009);
The water soluble form of SB 202190, a highly selective, potent inhibitor of p38 MAP kinase. SB-202190 is able to promote proliferation of C6 cells in lower concentration but induced apoptosis in higher levels. Studies show that SB202190 can protect neural function from ischemia/reperfusion injury and regulate the activation of Bcl-2 and Bax protein after ischemia/reperfusion in rat.
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