Ruxolitinib Phosphate
JAK1/JAK2抑制剂内标物
Ruxolitinib Phosphate
JAK1/JAK2抑制剂内标物
Ruxolitinib Phosphate
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产品编号： CRR702005
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CAS号： 1092939-17-7
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分子式：C17H21N6O4P
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分子量：404.36
英文别名：
(βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile Phosphate
SMILES：
OC[C@H]1O[C@@H](OC([C@]2(CCC[C@@]3([C@@]4(CC[C@]5(C(C[C@@]4(C5)CC[C@]23[H])=C)O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)[H])C)C)=O)[C@H](O)[C@@H](O)[C@@H]1O
参考文献：
Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);
The phosphate salt of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.
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