鲁斯可皂苷元
鲁斯可皂苷元
Ruscogenin
鲁斯可皂苷元
Ruscogenin
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产品编号： CRR701750
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CAS号： 472-11-7
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分子式：C27H42O4
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分子量：430.62
英文别名：
(1β,3β,25R)-Spirost-5-ene-1,3-diol; (25R)-Spirost-5-ene-1β,3β-diol; 25D-Spirost-5-ene-1β,3β-diol;
参考文献：
Huang, Y. et al.: Drug Dev. Res., 69, 196 (2008); Huang, Y. et al.: J. Pharmacol. Sci., 108, 198 (2008); Song, J. et al.: J. Pharmacol. Sci., 113, 409 (2010);
A major steroidal sapogenin from Radix ophiopogon japonicus with robust anti-inflammatory and anti-thrombotic activities. Studies suggest that it inhibits adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-α (TNF-α) in a concentration-dependent manner.
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