Ruboxistaurin-d6 Hydrochloride
JAK1/JAK2抑制剂内标物
Ruboxistaurin-d6 Hydrochloride
JAK1/JAK2抑制剂内标物
Ruboxistaurin-d6 Hydrochloride
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产品编号： CRR701527
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CAS号： 1794767-04-6
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分子式：C17H10D8N6
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分子量：314.41
英文别名：
β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; INCB 018424-d8;
参考文献：
Miller, J. et al.: Diabetes Metab. Rev., 13, 37 (1997);
Labelled Ruboxistaurin. Ruboxistaurin is a protein kinase C (PKC) β inhibitor, exhibits significant anti-angiogenic activity that reduces the response of vascular endothelial cells to stimulation by vascular endothelial growth factor (VEGF). Ruboxistaurin is used in treatment of diabetic microvascular complications.
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