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RTI-113
(1R,2S,3S,5S)-3-(4-氯苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸苯酯盐酸盐
RTI-113
  • 产品编号: CRR701110

  • CAS号: 141807-57-0

  • 分子式:C21H23Cl2NO2

  • 分子量:392.32

英文别名:
RTI 4229-113
参考文献:
Dworkin, S. et al.: Synapse, 30, 49 (1998); Negus, S.S. et al.: Pharmacol. Biochem. Behav., 91, 333 (2009); Cook, C. et al.: Eur. J. Pharmacol., 442, 93 (2002);
RTI-113 is a 3-phenyltropane analogue that acts as a potent and selective dopamine uptake inhibitor. RTI-113 has been shown to reduce cocaine self-administration at high occupancy of dopamine transporter. Studies suggest that RTI-113 and its analogs may be useful tools for developing potential agonist therapies for cocaine dependence.
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