Ro 67-4853
N-(9H-氧杂蒽-9-羰基)氨基甲酸丁酯
Ro 67-4853
N-(9H-氧杂蒽-9-羰基)氨基甲酸丁酯
Ro 67-4853
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产品编号： CRR637400
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CAS号： 302841-89-0
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分子式：C19H19NO4
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分子量：325.36
英文别名：
N-(9H-Xanthen-9-ylcarbonyl)carbamic Acid Butyl Ester
SMILES：
ClC1=CC=C(C(NC[C@@H]2OC(=O)N(C3C([2H])=C([2H])C(N4CCOCC4=O)=C([2H])C=3[2H])C2)=O)S1
参考文献：
Knoflach, et al.: Proc. Natl. Acad. Sci. 98, 13402 (2001), Hempstapat, et al.: Mol. Pharmacol., 70, 616 (2006),
Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptor. Ro 67-4853 exhibits activity at all group I receptors, including human and rat mGlu1 and rat mGlu5. Ro 67-4853 enhances the effects of (S)-DHPG in CA3 neurons.
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