雷帕霉素
雷帕霉素；(-)-雷帕霉素
Rapamycin
雷帕霉素；(-)-雷帕霉素
Rapamycin
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产品编号： CRR124000
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CAS号： 53123-88-9
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分子式：C51H79NO13
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分子量：914.17
英文别名：
(-)-Rapamycin;
熔点：
183-185°C
可溶性：
Methanol
性状：
White to Off-White Solid
SMILES：
CC(OC([C@@H](N[C@H](C(N1[C@H](C(=O)O)C[C@@H]2CCC[C@H]12)=O)C)CCC1=CC=CC=C1)=O)C
储存条件：
-20°C Freezer
参考文献：
Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),
A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
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