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N-(3-吡啶基)吲哚美辛酰胺
N-(3-吡啶基)吲哚美辛酰胺
N-(3-Pyridyl)indomethacin Amide
  • 产品编号: CPR995375

  • CAS号: 261755-29-4

  • 分子式:C24H20ClN3O3

  • 分子量:433.89

  • EINECES:202-864-6

英文别名:
N-(3-Pyridyl)-1-p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetamide; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-N-3-pyridinyl-1H-indole-3-acetamide;
SMILES:
N1C=CC=C(CO)C=1
参考文献:
Kalgutkar, A.S., et al.: J. Med. Chem., 43, 2860 (2000)
An aromatic amide of indomethacin recently reported to be a potent and selective reversible inhibitor of COX-2. Inhibits human recombinant COX-2 with IC50 of 0.1 uM.
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