PU-H71 三氟乙酸盐
HSP90抑制剂；6-氨基-8-[(6-碘-1,3-苯并二氧五环-5-基)硫]-N-(1-甲基乙基)-9H-嘌呤-9-丙胺三氟乙酸盐
PU-H71 Trifluoroacetic Acid
HSP90抑制剂；6-氨基-8-[(6-碘-1,3-苯并二氧五环-5-基)硫]-N-(1-甲基乙基)-9H-嘌呤-9-丙胺三氟乙酸盐
PU-H71 Trifluoroacetic Acid
-
产品编号： CPR840115
-
CAS号： 873436-91-0
-
分子式：C20H21F3In6O3S
-
分子量：609.38
英文别名：
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Trifluoroacetic Acid
参考文献：
Gewirth, D.T., et al.: J. Med. Chem., 49, 381 (2006), Taldone, T., et al.: Bioorh. Med. Chem., 17, 2225 (2009),
PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease.
搜索质检报告(COA)
搜索MSDS
