Pracinostat-d7
Pracinostat-d7
HDAC抑制剂内标物;山柰酚-3-O-β-D-(6-E-p-香豆酮基葡糖苷)-d7
Pracinostat-d7
HDAC抑制剂内标物;山柰酚-3-O-β-D-(6-E-p-香豆酮基葡糖苷)-d7
Pracinostat-d7
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产品编号: CPR699102
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CAS号: 1795137-15-3
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相关CAS号:929016-96-6(未标记)
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分子式:C20H23D7N4O2
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分子量:365.52
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EINECES:214-046-6
英文别名:
SB939-d7;Kaempferol 3-O-β-D-(6-E-p-Coumaroylglucoside)-d7
SMILES:
O=C1C2C(=CC=CC=2)C(=O)[N-]1.[K+]
参考文献:
Novotny-Diermayr, V. et al.: Mol. Cancer Therap., 9, 642 (2010); Razak, A.R.A. et al.: Br. J. Cancer, 104, 756 (2011); Novotny-Diermayr, V. et al.: Mol. Cancer Therap., 10, 1207 (2011);
Labelled Pracinostat. Pracinostat is a potent and orally active histone deacetylase (HDAC) inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. The selectivity of Pracinostat for tumor tissues makes it a promising therapeutic candidate for use in patients with advanced solid malignancies.
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