Pracinostat
HDAC抑制剂；山柰酚-3-O-β-D-(6-E-p-香豆酮基葡糖苷)
Pracinostat
HDAC抑制剂；山柰酚-3-O-β-D-(6-E-p-香豆酮基葡糖苷)
Pracinostat
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产品编号： CPR699100
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CAS号： 929016-96-6
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分子式：C20H30N4O2
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分子量：358.48
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EINECES：231-760-3
英文别名：
SB939；Kaempferol 3-O-β-D-(6-E-p-Coumaroylglucoside)
SMILES：
[K+].O=[Mn]([O-])(=O)=O
参考文献：
Novotny-Diermayr, V. et al.: Mol. Cancer Therap., 9, 642 (2010); Razak, A.R.A. et al.: Br. J. Cancer, 104, 756 (2011); Novotny-Diermayr, V. et al.: Mol. Cancer Therap., 10, 1207 (2011);
Pracinostat is a potent and orally active histone deacetylase (HDAC) inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer. The selectivity of Pracinostat for tumor tissues makes it a promising therapeutic candidate for use in patients with advanced solid malignancies.
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