Pluripotin
(ERK1, MAPK3)/RasGAP抑制剂
Pluripotin
(ERK1, MAPK3)/RasGAP抑制剂
Pluripotin
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产品编号： CPR632000
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CAS号： 839707-37-8
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分子式：C27H25F3N8O2
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分子量：550.53
英文别名：
Stemolecule SC 1；SC-1
SMILES：
OC1=CC=C(C=C1)CC(C(O)=O)NC(=O)C(C)(C)C
参考文献：
Yang, W. et al.: Stem Cells, 27, 383 (2009); Chen, S. et al.: Proc. Nat. Acad. Sci. USA., 103, 17266 (2006);
Pluripotin is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Pluripotin has been shown to maintain embryonic stem cell (ESC) self-renewal. When combined with leukemia inhibitory factor, Pluripotin greatly promotes derivation of embryonic stem cell lines from refractory strains.
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