磷酸哌喹
磷酸哌喹
Piperaquine Tetraphosphate
磷酸哌喹
Piperaquine Tetraphosphate
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产品编号： CPR480050
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CAS号： 911061-10-4
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分子式：C29H32Cl2N6.4H3Po4
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分子量：927.49
英文别名：
4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis[7-chloroquinoline] Tetraphosphate;
熔点：
>173° Cdec.)
可溶性：
DMOS, Methanol, Water
性状：
Off-White Solid
SMILES：
OC1C=CC(C2=C(C)C3C(=CC=C(O)C=3)N2CC2C=CC(OCCN3CCCCC3)=CC=2)=CC=1
储存条件：
Refrigerator
参考文献：
Nguyen, T.M.T. et al.: Tap Chi Duoc Hoc, 57, 22 (2007); Song, J. et al.: Malaria J., 10, 231 (2011);
Piperaquine is a 4-aminoquinoline derivative used as an antimalarial agent. Piperaquine interferes with physiological function of the food vacuole membrane of the trophozoites leading to autophagocytosis of the parasites. It is commonly used in combination with Dihydroartemisinin (D448360) for the treatment of multi-drug resistant falciparum malaria.
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