匹莫齐特
匹莫齐特
Pimozide
匹莫齐特
Pimozide
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产品编号： CPR447800
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CAS号： 2062-78-4
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分子式：C28H29F2N3O
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分子量：461.55
英文别名：
1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one;
1-[1-[4,4-Bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone; 1-[4,4-Bis(p-fluorophenyl)butyl]-4-(2-oxo-1-benzimidazolinyl)piperidine; NSC 170984; Orap; Primozi
参考文献：
Liu, J., et al.: Br. J. Pharmacol., 126, 245 (1999), Richelson, E., et al.: Life Sci., 68, 29 (2000), Santi, C., et al.: J. Neurosci., 22, 396 (2002), Mariot, P., et al.: J. Biol. Chem., 277, 10824 (2002), Nikonenko, I., et al.: Mol. Pharmacol., 68, 84 (2
Pimozide is a D2 dopamine receptor antagonist. Pimozide binds with high affinity to the cloned 5-HT7 receptor. Pimozide is also a Ca2+ channel antagonist. Pimozide is used as an antipsychotic.
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