PH-797804
p38MAP激酶抑制剂；3-(4-(2,4-二氟苄氧基)-3-溴-6-甲基-2-酮基吡啶-1(2H)-基)-N,4-二甲基苯甲酰胺
PH-797804
p38MAP激酶抑制剂；3-(4-(2,4-二氟苄氧基)-3-溴-6-甲基-2-酮基吡啶-1(2H)-基)-N,4-二甲基苯甲酰胺
PH-797804
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产品编号： CPR399150
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CAS号： 586379-66-0
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分子式：C22H19BrF2N2O3
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分子量：477.3
英文别名：
3-(4-(2,4-Difluorobenzyloxy)-3-bromo-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide
SMILES：
COC[C@H]([C@H](CC1C=CC(OC)=C(OC)C=1)COC)CC1C=CC(OC)=C(OC)C=1
参考文献：
Xing, L., et al.: ChemMedChem., 7, 273 (2012); Hope, H.R., et al.: J. Pharmacol. Exp. Thr., 331 (2009);
PH-797804 is a novel N-phenylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase derived from a racemic mixture as the more potent atropisomer and is also known to exerts anti-inflammatory properties.
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