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4-Phospho D-Erythronate
吡哆醛-5’-磷酸酯中间体;(2R,3R)-2,3-二羟基-4-(膦酰氧基)丁酸
4-Phospho D-Erythronate
  • 产品编号: CPR355000

  • CAS号: 57229-25-1

  • 分子式:C4H9O8P

  • 分子量:216.08

英文别名:
(2R,3R)-2,3-Dihydroxy-4-(phosphonooxy)butanoic Acid; [R-(R*,R*)]-2,3-Dihydroxy-4-(phosphonooxy)butanoic Acid;
参考文献:
Tanaka, N., et al.: J. Mol. Biol., 324, 519 (2002), Fitzpatrick, T., et al.: Biochem. J., 407, 1 (2007), Kalliri, E., et al.: J. Bacteriol., 190, 3793 (2008),
4-Phospho-D-erythronate is an intermediate in the synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Phosphorylated aldonic acids are strong inhibitors of 6-phosphogluconate dehydrogenase, and 4-phospho-D-erythronate (4PE) and 4-phospho-D-erythronohydroxamate are two of the strongest inhibitors of the Trypanosoma brucei enzyme.
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