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反式-4’-羟基苯环利定
反式-4’-羟基苯环己哌啶;反式-4’-羟基苯环利定
rac trans-4’-Hydroxy Phencyclidine
  • 产品编号: CPR336025

  • CAS号: 78165-07-8

  • 分子式:C17H25NO

  • 分子量:259.39

英文别名:
rac trans-4-Phenyl-4-(1-piperidinyl)cyclohexanol
参考文献:
Carroll, F.I. et al.: J. Med. Chem., 24, 1047 (1981); Baba, A. et al.: Neurosci. Lett., 182, 119 (1994); Shelnutt, S.R. et al.: J. Pharmacol. Exp. Therap., 290, 1292 (1999);
trans-4-Phenyl-4-(1-piperidinyl)cyclohexanol [(trans)-4-PPC] is the trans-isomer of the 4-hydroxy(cyclo) metabolite of Phencyclidine (P295502). Studies show that (trans)-4-PPC elicits dose-related increases in locomotor activity and rearing in mice, and (trans)-4-PPC may also be involved in psychotomimetic effects of PCP due to its inhibitory effect on DA uptake.
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