(6-{2-[3-(4-苯氨基甲酰)-5-(4-氟苯基)-2-异丙基-4-苯基-d5-吡咯-1-基]乙基}-2,2-二甲基-[1,3]-二恶烷-4-基)-乙酸叔丁酯
(6-{2-[3-(4-苯氨基甲酰)-5-(4-氟苯基)-2-异丙基-4-苯基-d5-吡咯-1-基]乙基}-2,2-二甲基-[1,3]-二恶烷-4-基)-乙酸叔丁酯
阿托伐他汀中间体内标物;(6-{2-[3-(4-苯氨基甲酰)-5-(4-氟苯基)-2-异丙基-4-苯基-d5-吡咯-1-基]乙基}-2,2-二甲基-[1,3]-二恶烷-4-基)-乙酸叔丁酯
(6-{2-[3-(4-Phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-d5-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
阿托伐他汀中间体内标物;(6-{2-[3-(4-苯氨基甲酰)-5-(4-氟苯基)-2-异丙基-4-苯基-d5-吡咯-1-基]乙基}-2,2-二甲基-[1,3]-二恶烷-4-基)-乙酸叔丁酯
(6-{2-[3-(4-Phenylcarbamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-d5-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
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产品编号: CPR319587
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CAS号: 265989-34-2
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分子式:C40H42D5FN2O5
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分子量:659.84
英文别名:
(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenyl-d5-amino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester;
可溶性:
Acetone, Chloroform, Dichloromethane, Ethyl Acetate
性状:
Light-Yellow Foamy Solid
SMILES:
C(/C1C=CC=CC=1)=C\CC
参考文献:
Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18. 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)
An deuterated intermediate of deuterated Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
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