PF-04217903 甲磺酸盐
c-Met抑制剂；4-[1-(6-喹啉甲基)-1H-1,2,3-三唑并[4,5-b]吡嗪-6-基]-1H-吡唑-1-乙醇甲磺酸盐
PF-04217903 Mesylate
c-Met抑制剂；4-[1-(6-喹啉甲基)-1H-1,2,3-三唑并[4,5-b]吡嗪-6-基]-1H-吡唑-1-乙醇甲磺酸盐
PF-04217903 Mesylate
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产品编号： CPR293990
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CAS号： 956906-93-7
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分子式：C20H20N8O4S
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分子量：468.49
英文别名：
4-[1-(6-Quinolinylmethyl)-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazole-1-ethanol Methanesulfonate
参考文献：
Eder, et al.: Clin. Cancer Res., 15, 2207 (2009); Timofeevski, et al.: Biochemistry, 48, 5339 (2009), Underiner, et al.: Anticancer Agents Med.Chem., 10, 7 (2010),
PF 04217903 is highly selective, high affinity c-Met inhibitor (Ki = 6-7 nM against wild type c-Met). Displays >1000-fold selectivity for c-Met over a panel of 208 kinases.
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