PF-573228
粘着斑激酶(FAK)抑制剂；3,4-二氢-6-[[4-[[[3-(甲磺酰)苯基]甲基]氨基]-5-三氟甲基-2-嘧啶基]氨基]-2(1H)-喹啉酮
PF 573228
粘着斑激酶(FAK)抑制剂；3,4-二氢-6-[[4-[[[3-(甲磺酰)苯基]甲基]氨基]-5-三氟甲基-2-嘧啶基]氨基]-2(1H)-喹啉酮
PF 573228
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产品编号： CPR293950
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CAS号： 869288-64-2
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分子式：C22H20F3N5O3S
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分子量：491.49
英文别名：
3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone
SMILES：
OCCN1CCN(CCCN2C3=CC=CC=C3S(=O)C3C=CC(=CC2=3)Cl)CC1
储存条件：
Refrigerator
参考文献：
Slack-Davis, J.K. et al.: J. Biol. Chem., 282, 14845 (2007); Hiscox, S. et al.: Breast Cancer Res. Treat., 125, 659 (2011);
A novel focal adhesion kinase inhibitor that has been shown to suppress the adverse phenotype of endocrine-resistant breast cancer cells and improve endocrine response in endocrine-sensitive cells.
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