PF-3644022-d4
2-甲氧基-N-(3-甲基-2-酮基-1,2,3,4-四氢喹唑啉-6-基)苯磺酰胺
PF-3644022-d4
2-甲氧基-N-(3-甲基-2-酮基-1,2,3,4-四氢喹唑啉-6-基)苯磺酰胺
PF-3644022-d4
-
产品编号： CPR293827
-
相关CAS号：1276121-88-0（未标记）
-
分子式：C16H17N3O4S
-
分子量：347.39
英文别名：
2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
参考文献：
Hegen, M., et al.: J. Immunol., 177, 1913 (2006); Anderson, D., et al.: J. Med. Chem., 50, 2647 (2007); Goldberg, D., et al.: Bioorg. Med. Chem. Lett., 18, 938 (2008); Burnette, B., et al.: Pharmacology, 84, 42 (2009); Mourey, et al.: J. Pharmacol. Exp. T
Labelled analogue of PF-3644022, a potent freely reversible ATP-competitive compound that inhibits MK2 activity (Ki = 3 nM) with good selectivity when profiled against 200 human kinases. PF-3644022 is a benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor α production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation.
搜索质检报告(COA)
搜索MSDS
