喷司他汀
喷司他丁；喷司他汀
Pentostatin
喷司他丁；喷司他汀
Pentostatin
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产品编号： CPR227350
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CAS号： 53910-25-1
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分子式：C11H16N4O4
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分子量：268.27
英文别名：
(8R)-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-imidazo[4,5-d][1,3]diazepin-8-ol; (R)-; 2'-DCF; 2'-Deoxycoformycin; CI 825; CL 67310465; Cl 825; Co-V; Co-Vidarabine; Coforin; NSC 218321; NSC 247520; Nipent; PD-ADI; Vira A Deaminase Inhibito
熔点：
225-227°C
可溶性：
DMSO
性状：
White Solid
SMILES：
FC1C=CC2C(C3CCN(CCC4C(=O)N5CCCC(OC(=O)CCCCCCCCCCCCCC)C5=NC=4C)CC3)=NOC=2C=1
储存条件：
Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
参考文献：
Rogler-Brown, T. et al.: Biochem. Pharmacol., 28, 201 (1979); Johnston, J.B. et al.: J. Natl. Canvcer Inst., 80, 765 (1988); Fortune, A.F. et al.: Leuk. and Lymph., 51, 839 (2010); Robak, T. et al.: Drugs, 69, 2415 (2009);
An adenosine deaminase inhibitor used as an anti-cancer therapeutic drug. Shown to be effective in the treatment of hairy cell leukemia as well as having use in the treatment of other types of cancer such as chronic lymphocytic leukemia.
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