PD-184161
MEK激酶抑制剂；5-溴-2-[(2-氯-4-碘苯基)氨基]-N-(环丙甲氧基)-3,4-二氟苯甲酰胺
PD-184161
MEK激酶抑制剂；5-溴-2-[(2-氯-4-碘苯基)氨基]-N-(环丙甲氧基)-3,4-二氟苯甲酰胺
PD-184161
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产品编号： CPR218100
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CAS号： 212631-67-9
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分子式：C17H13BrClF2In2O2
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分子量：557.56
英文别名：
5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
参考文献：
Yip-Schneider, M.T. et al.: J. Pharmacol. Exp. Therap., 329, 1063 (2009); Klein, P.J. et al.: Neoplasia, 8, 1 (2006); Yung, H.W. et al.: Biochem. Pharmacol., 68, 351 (2004);
A novel mitogen-activated protein kinase kinase (MEK) inhibitor shown to exhibit antitumor effects and suppress MEK-extracellular signal-related kinase signaling activity and cell proliferation in human hepatocellular carcinoma cells and in human hepatocellular carcinoma xenografts.
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