PD-123319-d6 双三氟乙酸盐
AT2受体拮抗剂内标物；(6S)-1-[[4-(二甲氨基-d6)-3-甲苯基]甲基]-5-(2,2-二苯基乙酰)-4,5,6,7-四氢-1H-咪唑并[4,5-c]吡啶-6-羧酸双三氟乙酸盐水合物
PD-123319-d6 Bis(trifluoroacetate) Salt Hydrate
AT2受体拮抗剂内标物；(6S)-1-[[4-(二甲氨基-d6)-3-甲苯基]甲基]-5-(2,2-二苯基乙酰)-4,5,6,7-四氢-1H-咪唑并[4,5-c]吡啶-6-羧酸双三氟乙酸盐水合物
PD-123319-d6 Bis(trifluoroacetate) Salt Hydrate
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产品编号： CPR217477
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CAS号： 1346603-57-3
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相关CAS号：130663-39-7（未标记）
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分子式：C31H26D6N4O3.2C2Hf3O2.XH2O
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分子量：742.69
英文别名：
(6S)-1-[[4-(Dimethylamino-d6)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid Bis(trifluoroacetate) Salt Hydrate; (S)-(+)-PD 123319-d6 Bis(trifluoroacetate) Salt Hydrate;
参考文献：
Carmeiros-Ramos, M.S. et al.: Bas. Res, Cardiol., 105, 325 (2010); Kagawa, T. et al.: Nephrol., 13, 309 (2008); Cohen, E.P. et al.: Transl. Res., 150, 106 (2007);
A labelled selective and potent non-peptide angiotensin II type 2 (AT2) receptor antagonist. Potential treatment of cardiac hypertrophy as blockage of AT2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. Studies show that it has protective effect against tumor necrosis factor-α-induced damage to human renal proximal tubular epithelial cells
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