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奥美普林-d6
奥美普林-d6
Ormetoprim-d6
  • 产品编号: COR686802

  • CAS号: 1346602-49-0

  • 分子式:C14H12D6N4O2

  • 分子量:280.36

  • EINECES:206-254-0

英文别名:
2,4-Diamino-5-(6-methylveratryl)pyrimidine-d6; 2,4-Diamino-5-[2-methyl-4,5- (dimethoxy-d6)benzyl]pyrimidine; Diamino-5-(6-methylveratryl)pyrimidine-d6; NSC 95072-d6; Ormethoprim-d6; Ro 5-9754-d6;
SMILES:
OCCN1CCN(CCCN2C3=CC=CC=C3C=CC3=CC=CC=C23)CC1
参考文献:
Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),
Labelled O686800 (O686800). It is a potent and selective inhibitor of bacterial dihydrofolate reductase, the enzyme responsible for the NADPH-dependent reduction of 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate. Antibacterial.
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