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NU6102
CDK1抑制剂;CDK2抑制剂;CDK7抑制剂;4-[[6-(环己基甲氧基)-9H-嘌呤-2-基]氨基]苯磺酰胺
NU6102
  • 产品编号: CNR925290

  • CAS号: 444722-95-6

  • 分子式:C18H22N6O3S

  • 分子量:402.47

英文别名:
4-[[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino]benzenesulfonamide
SMILES:
C1C=CC(P(C2C=CC=CC=2)(=NC2=CC=CC(N=P(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)=C2)C2C=CC=CC=2)=CC=1
参考文献:
Heiser, L.M., Proceeding. National. Academy. Sci. U.S.A., 109, 2924 (2012); Anderson, P.C., J. Medn. Chem., 55, 1926 (2012); Takeuchi, Y., J. Veterinary. Med. Sci., 73, 1295, (2011); Marchetti, F., et al.: Org. Biomolec. Chem., 8, 2397 (2010);
NU6102 is a known potent inhibitor of CDK1, CDK2 and CDK7. Cyclin-dependent kinases play a key role in the regulation of cell division which is controlled by the phosphorylation of distinct substrates in different phases of the cell cycle. In any circumst
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