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Noditinib-1
1-[(4-甲苯基)磺酰]-1H-苯并咪唑-2-胺
Noditinib-1
  • 产品编号: CNR634200

  • CAS号: 799264-47-4

  • 分子式:C14H13N3O2S

  • 分子量:287.34

  • EINECES:229-633-2

英文别名:
1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-amine
SMILES:
OC1C([N+]([O-])=O)=CC(C=O)=CC=1OC
参考文献:
Khan, P.M. et al.: ACS Med. Chem. Lett., 2, 780 (2011);
Noditinib-1 is a potent and selective inhibitor of NOD1-induced NF-κB activation. Mutations in NOD proteins have been associated with various inflammatory diseases and Noditinib-1 shows promise as a potential therapeutic agent.
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