尼替西农
尼替西农
Nitisinone
尼替西农
Nitisinone
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产品编号： CNR490135
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CAS号： 104206-65-7
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分子式：C14H10F3NO5
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分子量：329.23
英文别名：
2-[2-Nitro-4-(trifluoromethyl)benzoyl]-
熔点：
129-131°C
可溶性：
Chloroform, Ethyl Acetate
性状：
Light Brown Solid
SMILES：
COCCOC(C1=C(C)NC(C)=C(C(OC(C)C)=O)C1C1=CC=CC([N+]([O-])=O)=C1)=O
储存条件：
-20°C Freezer
参考文献：
Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),
Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.
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