β-烟酰胺单核苷酸
β-烟酰胺单核苷酸
β-烟酰胺单核苷酸;β-烟酰胺核苷酸
β-Nicotinamide Mononucleotide
β-烟酰胺单核苷酸;β-烟酰胺核苷酸
β-Nicotinamide Mononucleotide
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产品编号: CNR407765
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CAS号: 1094-61-7
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分子式:C11H15N2O8P
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分子量:334.22
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EINECES:206-359-1
英文别名:
β-D-NMN;β-NMN;Nicotinamide Ribotide
SMILES:
CC1=CC(C)=NC(O)=N1.O=[N+](C1=CC=C(NC(NC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1)[O-]
参考文献:
Yoshino, J. et al.: Cell Metab., 14, 528 (2011); Caton, P.W. et al.: Diabetologia, 54, 3083 (2011); Formentini, L. et al.: BIochem. Pharmacol., 77, 1612 (2009);
A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and rest
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