来那替尼-d6
来那替尼-d6
来那替尼-d6
Neratinib-d6
来那替尼-d6
Neratinib-d6
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产品编号: CNR390092
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CAS号: 1259519-18-0
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相关CAS号:698387-09-6-unlabelled
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分子式:C30H23D6ClN6O3
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分子量:563.08
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EINECES:215-773-1
英文别名:
(2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino-d6)-2-butenamide; HKI 272-d6;
SMILES:
OS(=O)(O)=O.NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O
参考文献:
Vogel, C., et al.: J. Clin. Oncol., 20, 719 (2002),
Labelled Neratinib (N390090). An oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer. Antitumor agent
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