trans-Ned-19-d8
NAADP拮抗剂内标物；(1R,3S)-1-[3-[[4-(2-氟苯基)-1-哌嗪基]甲基]-4-甲氧苯基]-2,3,4,9-四氢-1H-吡啶并[3,4-b]吲哚-3-羧酸-d8
trans-Ned-19-d8
NAADP拮抗剂内标物；(1R,3S)-1-[3-[[4-(2-氟苯基)-1-哌嗪基]甲基]-4-甲氧苯基]-2,3,4,9-四氢-1H-吡啶并[3,4-b]吲哚-3-羧酸-d8
trans-Ned-19-d8
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产品编号： CNR388752
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相关CAS号：1354235-96-3（未标记）
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分子式：C30H23D8FN4O3
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分子量：522.64
英文别名：
(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-(piperazinyl-d8)]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;
SMILES：
O.[Na+].O=C(/C=C1\CCCC2=CC=CC=C2C\1O)[O-]
参考文献：
Rosen, D. et al.: J. Biol. Chem., 284, 34930 (2009); Naylor, E. et al.: Nat. Chem. Biol., 5, 220 (2009); Thai, T.L. et al.: Am. J. Physiol. Renal Physiol., 297, F510 (2009);
Labelled trans-Ned-19, a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be
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